This interview with Giorgio Vallortigara, professor of Neuroscience at the Centre for Mind-Brain Sciences at the University of Trento and one of the world’s leading experts on animal intelligence, revolves around the role played by the notion of immersed sense in his investigations. Among the topics discussed: the significance of recent discoveries about how human and animal brains work; the inadequacy of the way the human-animal frontier is usually drawn; the relationship between human and natural sciences; the pragmatic quality of human intelligence; natural selection as the overarching principle of all life phenomena; the impact of the AI revolution on our attempts at understanding how biological organisms create meaning; and the ultimate meaning of the scientific enterprise.